This Request for Expressions of Interest seeks responses from vendors and/or vendor consortia to develop and operate a National Primary Care Data Service. General Practice collectively holds a wealth of information on the health and wellbeing of the majority of New Zealanders. Only a small fraction of this data is currently assembled in any meaningful way to support the sector’s understanding of population health, quality improvement initiatives and health system planning, including the value of investment options. Primary Care Networks (PCNs) currently collect practice data individually for a variety of purposes and in a variety of infrastructures, but without the ability to compare or contrast this information across PCNs. There is limited capacity to combine this data with other national, regional or local datasets to support clear and meaningful changes that will improve the performance of the New Zealand health and social systems and the wellbeing of all New Zealanders. The majority of PCNs, having recognised the benefits of establishing a National Primary Care Data Service (NPCDS), have jointly funded this Expression of Interest with a view to gauging the capacity, capability, cost and feasibility of implementing a NPCDS for the sector. This process aims to enable the selection of a vendor partner or consortium to work with the sector to progress the NPCDS into being a reality for New Zealand. Submissions addressing the development or the operational aspects of the requirement alone will be considered, but comprehensive submissions will be preferred.